This conference seeks to bring together international researchers to present papers and generate discussions on the recent trends and developments of computing, communications, and science information systems. The integration of artificial intelligence (AI) and digital twin technology has revolutionized the way we design, operate, and maintain physical systems. In today's digital era, the combination of AI and digital twin allows us to create virtual replicas of real-world systems, which can be analyzed and optimized using sophisticated algorithms and machine learning techniques.